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beta Catenin antibody (C-Term)

The Mouse Monoclonal anti-beta Catenin antibody is suitable to detect beta Catenin in samples from Human, Mouse and Chicken. It has been validated for WB, FACS, IF and IHC (p).
Catalog No. ABIN4949473
$640.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 2 to 3 Business Days

Quick Overview for beta Catenin antibody (C-Term) (ABIN4949473)

Target

See all beta Catenin (CATNB) Antibodies
beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivity

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Human, Mouse, Chicken

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This beta Catenin antibody is un-conjugated

Application

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

5H10
  • Binding Specificity

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    C-Term

    Purification

    Protein G affinity chromatography

    Immunogen

    A C-terminal 100 amino acid segment from chicken beta-Catenin was used as the immunogen for the Beta Catenin antibody.

    Isotype

    IgG1 kappa
  • Application Notes

    Optimal dilution of the Beta Catenin antibody to be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,WB: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Preservative

    Azide free

    Storage

    4 °C,-20 °C

    Storage Comment

    Store the Beta Catenin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    Alternative Name

    Beta Catenin

    Background

    Beta Catenin is a dual function protein, regulating the coordination of cell-cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. Beta catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. It is a member of the catenin protein family and homologous to gamma-Catenin, also known as plakoglobin. Beta-Catenin is widely expressed in many tissues. In cardiac muscle, it localizes to adherens junctions in intercalated disc structures, which are critical for electrical and mechanical coupling between adjacent cardiomyocyte. [Wiki]

    Pathways

    Peptide Hormone Metabolism
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