CD44v4 antibody

Catalog No. ABIN4949522

The Mouse Monoclonal anti-CD44v4 antibody (Clone CD44v4-1219) (ABIN4949522) specifically detects CD44v4 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for CD44v4 antibody (ABIN4949522)

Target: CD44v4

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CD44v4-1219

Product Details

Purpose: CD44v4 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: An amino acid sequence from the variant 4 domain of CD44 was used as the immunogen for the CD44v4 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Titering of the CD44v4 antibody may be required for optimal performance.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD44v4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details

Target: CD44v4

Background: This antibody recognizes an epitope encoded by exon v4 on the variant portion of human CD44. The CD44 Molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. It is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.

UniProt: P16070