Interferon gamma antibody

Catalog No. ABIN4949769

This Mouse Monoclonal antibody specifically detects Interferon gamma in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Interferon gamma antibody (ABIN4949769)

Target: Interferon gamma (IFNG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Interferon gamma antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: IFNG-466

Product Details anti-Interferon gamma Antibody

Purpose: IFN gamma Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Human recombinant protein was used as the immunogen for the IFN gamma antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the IFN gamma antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the IFN gamma antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Interferon gamma

Target: Interferon gamma (IFNG)

Alternative Name: IFN gamma

Background: Recognizes a protein of 20-25 kDa, identified as human interferon. This mAb is specific to human IFNg and recognizes both recombinant and native human IFNg. T lymphocytes and NK cells mainly produce IFNg. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFNa/b (type I interferon).

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy