Plakophilin 1 antibody (N-Term)

Catalog No. ABIN4949852

This anti-Plakophilin 1 antibody is a Mouse Monoclonal antibody detecting Plakophilin 1 in WB and IF. Suitable for Human and Mouse.

Quick Overview for Plakophilin 1 antibody (N-Term) (ABIN4949852)

Target: Plakophilin 1 (PKP1)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Plakophilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 10B2

Product Details anti-Plakophilin 1 Antibody

Binding Specificity: AA 1-27, N-Term

Purification: Protein G affinity chromatography

Immunogen: A N-terminal human recombinant protein fragment was used as the immunogen for the Plakophilin 1 antibody. Its epitope maps to between amino acids 1-27 of human PKP1.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal dilution of the Plakophilin 1 antibody should be determined by the researcher.\. WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Plakophilin 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for Plakophilin 1

Target: Plakophilin 1 (PKP1)

Alternative Name: Plakophilin 1

Background: Recognizes a protein of 75  kDa, identified as Plakophilin 1 (PKP1). Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. PKP1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). PKP2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.