Plakophilin 1 antibody

Catalog No. ABIN7467140

Product Details anti-Plakophilin 1 Antibody

Target: Plakophilin 1 (PKP1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plakophilin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Plakophilin 1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Plakophilin 1

Target: Plakophilin 1 (PKP1)

Alternative Name: plakophilin 1 (PKP1 Products)

Synonyms: PKP1 antibody, fb30d08 antibody, wu:fb30d08 antibody, AI528551 antibody, B6P antibody, plakophilin 1 antibody, plakophilin 1b antibody, PKP1 antibody, pkp1b antibody, Pkp1 antibody

Background: Plakophilin 1 , B6P,This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. [provided by RefSeq]

Molecular Weight: 83 kDa

Gene ID: 5317

UniProt: Q13835