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TIMP2 antibody (N-Term)

The Mouse Monoclonal anti-TIMP2 antibody (Clone SPM356) (ABIN4949918) specifically detects TIMP2 in IHC (p). The antibody is reactive with Human samples.
Catalog No. ABIN4949918
$640.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for TIMP2 antibody (N-Term) (ABIN4949918)

Target

See all TIMP2 Antibodies
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reactivity

  • 175
  • 126
  • 96
  • 49
  • 46
  • 44
  • 44
  • 13
  • 13
  • 12
  • 10
  • 7
  • 5
  • 3
  • 1
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  • 1
  • 1
Human

Host

  • 156
  • 65
  • 8
  • 3
  • 1
Mouse

Clonality

  • 127
  • 106
Monoclonal

Conjugate

  • 99
  • 22
  • 9
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
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  • 4
  • 4
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
This TIMP2 antibody is un-conjugated

Application

  • 142
  • 92
  • 40
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  • 20
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  • 11
  • 6
  • 2
  • 1
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  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade

Carrier-free

Clone

SPM356
  • Binding Specificity

    • 43
    • 40
    • 15
    • 15
    • 14
    • 14
    • 11
    • 7
    • 5
    • 3
    • 3
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    • 2
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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Purpose

    TIMP2 Antibody (azide and preservative free)

    Purification

    Protein G affinity chromatography

    Immunogen

    An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

    Isotype

    IgG2a, kappa
  • Application Notes

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TIMP2 antibody to be titered up or down for optimal performance.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Preservative

    Azide free

    Storage

    4 °C,-20 °C

    Storage Comment

    Store the TIMP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • Target

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    Alternative Name

    TIMP2

    Background

    It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

    UniProt

    P16035

    Pathways

    cAMP Metabolic Process
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