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PKC eta antibody (AA 30-389)

PRKCH Reactivity: Human WB, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4952175
  • Target See all PKC eta (PRKCH) Antibodies
    PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))
    Binding Specificity
    • 16
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-389
    Reactivity
    • 58
    • 30
    • 18
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 68
    • 4
    Rabbit
    Clonality
    • 67
    • 4
    Polyclonal
    Conjugate
    • 41
    • 9
    • 8
    • 6
    • 4
    • 4
    This PKC eta antibody is un-conjugated
    Application
    • 62
    • 46
    • 31
    • 16
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    Antigen affinity
    Immunogen
    Amino acids 30-389 of human PKC eta were used as the immunogen for the PKC eta antibody.
    Isotype
    IgG
    Top Product
    Discover our top product PRKCH Primary Antibody
  • Application Notes
    Optimal dilution of the PKC eta antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,FACS: 1-3 μg/10^6 cells
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the PKC eta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))
    Alternative Name
    PKC eta (PRKCH Products)
    Synonyms
    PKC-L antibody, PKCL antibody, PRKCL antibody, nPKC-eta antibody, Pkch antibody, pkc-eta antibody, PRKCH antibody, prkch antibody, si:ch211-212g7.5 antibody, zgc:172124 antibody, protein kinase C eta antibody, protein kinase C, eta antibody, protein kinase C eta L homeolog antibody, protein kinase C, eta, b antibody, protein kinase C, eta, a antibody, protein kinase C epsilon antibody, PRKCH antibody, Prkch antibody, prkch.L antibody, prkchb antibody, prkcha antibody, prkch antibody, PRKCE antibody
    Background
    PRKCH is also known as PKC eta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Also, PKC family members serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. And it is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.
    UniProt
    P24723
    Pathways
    Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling
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