CGRP antibody (AA 56-84)
Quick Overview for CGRP antibody (AA 56-84) (ABIN3030254)
Target
See all CGRP (CALCA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 56-84
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Purification
- Purified
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Immunogen
- A portion of amino acids 56-84 from the human protein was used as the immunogen for this CGRP antibody.
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Isotype
- IgM
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Application Notes
- The stated application concentrations are suggested starting amounts. Titration of the CGRP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:100-1:250
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at 4°C for up to one month. For long term, aliquot the CGRP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))
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Alternative Name
- CGRP
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Background
- Calcitonin/Calcitonin Gene Related Peptide/CGRP/CALCA causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Katacalcin (a cleavage product) is a potent plasma calcium-lowering peptide. [UniProt]
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UniProt
- P01258
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Pathways
- Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour
Target
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