MUC20 antibody (AA 61-90)

Catalog No. ABIN3028849

This Rabbit Polyclonal antibody specifically detects MUC20 in WB, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for MUC20 antibody (AA 61-90) (ABIN3028849)

Target: MUC20 (Mucin 20, Cell Surface Associated (MUC20))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC20 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-MUC20 Antibody

Binding Specificity: AA 61-90

Purpose: MUC20 Antibody

Purification: Purified

Immunogen: A portion of amino acids 61-90 from the human protein was used as the immunogen for this MUC20 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the MUC20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MUC20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MUC20

Target: MUC20 (Mucin 20, Cell Surface Associated (MUC20))

Alternative Name: MUC20

Background: MUC20 may regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. [UniProt]

UniProt: Q8N307