HSP90 antibody (C-Term)

Catalog No. ABIN3031164

The Rabbit Polyclonal anti-HSP90 antibody (ABIN3031164) specifically detects HSP90 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HSP90 antibody (C-Term) (ABIN3031164)

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP90 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HSP90 Antibody

Binding Specificity: AA 644-677, C-Term

Purpose: HSP-90 Antibody / HSP90AA1

Cross-Reactivity (Details): Expected species reactivity: Bovine, Chicken, Hamster, Pig, Primate, Rabbit, Zebrafish

Purification: Antigen affinity

Immunogen: This HSP-90 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 644-677 amino acids from the C-terminal region of human HSP90AA1.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the HSP-90 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4oC for up to one month. For long term, aliquot the HSP-90 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSP90

Target: HSP90 (Heat Shock Protein 90 (HSP90))

Alternative Name: HSP-90

Background: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

UniProt: P07900

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals