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HTRA2 antibody

HTRA2 Reactivity: Human WB, IP Host: Mouse Monoclonal 8G11-4B8-4F10-G5 unconjugated
Catalog No. ABIN4953263
  • Target See all HTRA2 Antibodies
    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
    Reactivity
    • 109
    • 71
    • 67
    • 2
    • 1
    Human
    Host
    • 99
    • 11
    Mouse
    Clonality
    • 90
    • 20
    Monoclonal
    Conjugate
    • 41
    • 10
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HTRA2 antibody is un-conjugated
    Application
    • 69
    • 44
    • 28
    • 26
    • 26
    • 19
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Purification
    Protein G affinity
    Immunogen
    A human recombinant protein was used as the immunogen for this HtrA2 antibody.
    Clone
    8G11-4B8-4F10-G5
    Isotype
    IgG1
    Top Product
    Discover our top product HTRA2 Primary Antibody
  • Application Notes
    The stated application concentrations are suggested starting points. Titration of the HtrA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,Immunoprecipitation: suitable
    Restrictions
    For Research Use only
  • Buffer
    Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
    Storage
    -20 °C
    Storage Comment
    Store the HtrA2 antibody at -20°C.
  • Target
    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
    Alternative Name
    HtrA2 / Omi (HTRA2 Products)
    Synonyms
    CG8464 antibody, DmHtrA2 antibody, Dmel\\CG8464 antibody, HtrA2/Omi antibody, Omi antibody, dOmi antibody, domi antibody, htrA2 antibody, omi antibody, HTRA2 antibody, PRSS25 antibody, OMI antibody, PARK13 antibody, AI481710 antibody, Prss25 antibody, mnd2 antibody, HTRA2-related serine protease antibody, HtrA serine peptidase 2 antibody, HtrA2 antibody, HTRA2 antibody, htra2 antibody, Htra2 antibody
    Background
    Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. [UniProt]
    UniProt
    O43464
    Pathways
    Positive Regulation of Endopeptidase Activity
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