PKC alpha antibody
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- Target See all PKC alpha (PKCa) Antibodies
- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
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Reactivity
- Rat, Primate
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PKC alpha antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity (Details)
- Expected species reactivity: Human
- Purification
- Protein G affinity
- Immunogen
- A synthetic PKC alpha/aPKC peptide was used as the immunogen for the PKC alpha antibody.
- Clone
- 3G11-G11-G11
- Isotype
- IgG2a
- Top Product
- Discover our top product PKCa Primary Antibody
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- Application Notes
- The stated application concentrations are suggested starting points. Titration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Restrictions
- For Research Use only
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- Buffer
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
- Storage
- -20 °C
- Storage Comment
- Store the PKC alpha antibody at -20°C.
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- Target
- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
- Alternative Name
- PRKCA / PKC alpha (PKCa Products)
- Synonyms
- pkc-alpha antibody, pkcalpha antibody, im:7139045 antibody, si:dkey-8l19.1 antibody, LOC100219195 antibody, AAG6 antibody, PKC-alpha antibody, PKCA antibody, PRKACA antibody, AI875142 antibody, Pkca antibody, PKRCA antibody, protein kinase C alpha antibody, protein kinase C, alpha L homeolog antibody, protein kinase C, alpha antibody, PRKCA antibody, prkca.L antibody, prkca antibody, Prkca antibody
- Background
- This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
- UniProt
- P17252
- Pathways
- WNT Signaling, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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