PKC alpha antibody
Quick Overview for PKC alpha antibody (ABIN4953283)
Target
See all PKC alpha (PKCa) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- PKC alpha Antibody / aPKC
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Cross-Reactivity (Details)
- Expected species reactivity: Human
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Purification
- Protein G affinity
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Immunogen
- A synthetic PKC alpha/aPKC peptide was used as the immunogen for the PKC alpha antibody.
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Isotype
- IgG2a
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anti-Protein Kinase C, alpha (PKCa) (AA 563-672) antibody
PKCa Reactivity: Human WB, ELISA, IF, IHC (p), PLA Host: Mouse Monoclonal 2F11 unconjugated
anti-Protein Kinase C, alpha (PKCa) antibodyKD Validated PKCa Reactivity: Human WB, ICC, FACS, IF (p) Host: Rabbit Monoclonal 23GB1690 unconjugated Recombinant Antibody
anti-Protein Kinase C, alpha (PKCa) (pThr497) antibodyKD Validated PKCa Reactivity: Human WB, FACS, IF (p) Host: Rabbit Monoclonal 23GB4955 unconjugated Recombinant Antibody
anti-Protein Kinase C, alpha (PKCa) antibodyKD Validated PKCa Reactivity: Human WB, FACS, IF (p) Host: Rabbit Monoclonal 24GB4475 unconjugated Recombinant Antibody
anti-Protein Kinase C, alpha (PKCa) (AA 153-342) antibodyPKCa Reactivity: Human, Mouse, Rat WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase C, alpha (PKCa) (AA 299-329), (C-Term) antibodyPKCa Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB01012 unconjugated
anti-Protein Kinase C, alpha (PKCa) (AA 299-329) antibodyPKCa Reactivity: Human WB, IHC, ELISA, IF, FACS Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase C, alpha (PKCa) (pThr638) antibodyPKCa Reactivity: Human, Mouse WB, IHC (p), FACS, IF (cc) Host: Rabbit Monoclonal 4B3 unconjugated
anti-Protein Kinase C, alpha (PKCa) (pThr638) antibodyPKCa Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Protein Kinase C, alpha (PKCa) (pSer657) antibodyKD Validated PKCa Reactivity: Human WB, FACS Host: Rabbit Monoclonal 23GB1055 unconjugated Recombinant Antibody
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In PBS with 50 % glycerol and 0.03 % ProClin 300
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store the PKC alpha antibody at -20oC.
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- PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
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Alternative Name
- PKC alpha
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Background
- This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
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UniProt
- P17252
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Pathways
- WNT Signaling, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
Target
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