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PKC alpha antibody

PKCa Reactivity: Rat, Primate WB Host: Mouse Monoclonal 3G11-G11-G11 unconjugated
Catalog No. ABIN4953283
  • Target See all PKC alpha (PKCa) Antibodies
    PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
    Reactivity
    • 178
    • 90
    • 67
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Rat, Primate
    Host
    • 174
    • 11
    • 1
    Mouse
    Clonality
    • 140
    • 45
    Monoclonal
    Conjugate
    • 95
    • 15
    • 13
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKC alpha antibody is un-conjugated
    Application
    • 127
    • 71
    • 53
    • 33
    • 22
    • 20
    • 17
    • 15
    • 14
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity (Details)
    Expected species reactivity: Human
    Purification
    Protein G affinity
    Immunogen
    A synthetic PKC alpha/aPKC peptide was used as the immunogen for the PKC alpha antibody.
    Clone
    3G11-G11-G11
    Isotype
    IgG2a
    Top Product
    Discover our top product PKCa Primary Antibody
  • Application Notes
    The stated application concentrations are suggested starting points. Titration of the PKC alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Buffer
    Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
    Storage
    -20 °C
    Storage Comment
    Store the PKC alpha antibody at -20°C.
  • Target
    PKC alpha (PKCa) (Protein Kinase C, alpha (PKCa))
    Alternative Name
    PRKCA / PKC alpha (PKCa Products)
    Synonyms
    pkc-alpha antibody, pkcalpha antibody, im:7139045 antibody, si:dkey-8l19.1 antibody, LOC100219195 antibody, AAG6 antibody, PKC-alpha antibody, PKCA antibody, PRKACA antibody, AI875142 antibody, Pkca antibody, PKRCA antibody, protein kinase C alpha antibody, protein kinase C, alpha L homeolog antibody, protein kinase C, alpha antibody, PRKCA antibody, prkca.L antibody, prkca antibody, Prkca antibody
    Background
    This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
    UniProt
    P17252
    Pathways
    WNT Signaling, TCR Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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