SIRT3 antibody (AA 304-334)

Catalog No. ABIN3032591

The Rabbit Polyclonal anti-SIRT3 antibody has been validated for WB, IHC and ELISA. It is suitable to detect SIRT3 in samples from Human, Mouse and Hamster.

Quick Overview for SIRT3 antibody (AA 304-334) (ABIN3032591)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reactivity: Human, Mouse, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-SIRT3 Antibody

Binding Specificity: AA 304-334

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 304-334 from the mouse protein was used as the immunogen for this SIRT3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C for up to one month. For long term, aliquot the SIRT3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Alternative Name: SIRT3

Background: SIRT3 is an NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, PDHA1, SOD2, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels. [UniProt]

UniProt: Q8R104