SIRT6 antibody
-
- Target See all SIRT6 Antibodies
- SIRT6 (Sirtuin 6 (SIRT6))
-
Reactivity
- Human, Mouse, Rat, Primate
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This SIRT6 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Purification
- Protein G affinity
- Immunogen
- A human recombinant protein was used as the immunogen for this SIRT6 antibody.
- Clone
- 6C9-D10-D3
- Isotype
- IgG1
- Top Product
- Discover our top product SIRT6 Primary Antibody
-
-
- Application Notes
- The stated application concentrations are suggested starting points. Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,ICC/IF: 1:100,Immunoprecipitation: suitable
- Restrictions
- For Research Use only
-
- Buffer
- Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
- Storage
- -20 °C
- Storage Comment
- Store the SIRT6 antibody at -20°C.
-
- Target
- SIRT6 (Sirtuin 6 (SIRT6))
- Alternative Name
- SIRT6 (SIRT6 Products)
- Synonyms
- 2810449N18Rik antibody, AI043036 antibody, Sir2l6 antibody, SIR2L6 antibody, zgc:86729 antibody, sirtuin 6 antibody, sirtuin 6 S homeolog antibody, Sirt6 antibody, SIRT6 antibody, sirt6.S antibody, sirt6 antibody
- Background
- NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. [UniProt]
- UniProt
- Q8N6T7
-