CXCR4 antibody (AA 50-79)
Quick Overview for CXCR4 antibody (AA 50-79) (ABIN3030512)
Target
See all CXCR4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 50-79
-
Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Rat, Bovine, Pig, Primate
-
Purification
- Antigen affinity purified
-
Immunogen
- A portion of amino acids 50-79 from the human protein was used as the immunogen for this anti-CXCR4 antibody.
-
Isotype
- Ig Fraction
-
-
-
-
Application Notes
- Titration of the anti-CXCR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Aliquot the anti-CXCR4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
-
Alternative Name
- CXCR4
-
Background
- This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
-
UniProt
- P61073
-
Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
Target
-