ASAH2 antibody (AA 734-762)
Quick Overview for ASAH2 antibody (AA 734-762) (ABIN3031924)
Target
See all ASAH2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 734-762
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Purpose
- ASAH2 Antibody
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 734-762 from the human protein was used as the immunogen for this ASAH2 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the ASAH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the ASAH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))
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Alternative Name
- ASAH2
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Background
- Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger (see MIM 603730) (Mitsutake et al., 2001 [PubMed 11328816]).
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UniProt
- Q9NR71
Target
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