ATG13 antibody (AA 1-30)

Catalog No. ABIN3030086

The Rabbit Polyclonal anti-ATG13 antibody has been validated for WB, ELISA and IHC. It is suitable to detect ATG13 in samples from Human.

Quick Overview for ATG13 antibody (AA 1-30) (ABIN3030086)

Target: ATG13 (Autophagy Related 13 (ATG13))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ATG13 Antibody

Binding Specificity: AA 1-30

Cross-Reactivity (Details): Expected species reactivity: Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this ATG13 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ATG13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ATG13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ATG13

Target: ATG13 (Autophagy Related 13 (ATG13))

Alternative Name: ATG13

Background: ATG13 is an autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. [UniProt]

UniProt: O75143

Pathways: PI3K-Akt Signaling, Autophagy