Aurora Kinase B antibody (AA 283-313)

Catalog No. ABIN3030077

The Rabbit Polyclonal anti-Aurora Kinase B antibody has been validated for WB, ELISA and IHC. It is suitable to detect Aurora Kinase B in samples from Human and Mouse.

Quick Overview for Aurora Kinase B antibody (AA 283-313) (ABIN3030077)

Target: Aurora Kinase B (AURKB)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora Kinase B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Aurora Kinase B Antibody

Binding Specificity: AA 283-313

Purification: Purified

Immunogen: A portion of amino acids 283-313 from the human protein was used as the immunogen for this Aurora B antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Aurora B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Aurora B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Alternative Name: Aurora B

Background: Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. STK12 (Aurora kinase B) localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A localizes to centrosomes

UniProt: Q96GD4

Pathways: TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades