BID antibody (AA 39-68)

Catalog No. ABIN3030161

The Rabbit Polyclonal anti-BID antibody is suitable to detect BID in samples from Mouse. It has been validated for WB, IHC, ELISA and FACS.

Quick Overview for BID antibody (AA 39-68) (ABIN3030161)

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BID antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-BID Antibody

Binding Specificity: AA 39-68

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 39-68 from the mouse protein was used as the immunogen for this Bid antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Bid antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Bid antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for BID

Target: BID (BH3 Interacting Domain Death Agonist (BID))

Alternative Name: Bid

Background: Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.

UniProt: P70444

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity