BID antibody (AA 39-68)
Quick Overview for BID antibody (AA 39-68) (ABIN3030161)
Target
See all BID AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 39-68
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Purpose
- Bid Antibody
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 39-68 from the mouse protein was used as the immunogen for this Bid antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the Bid antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Bid antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BID (BH3 Interacting Domain Death Agonist (BID))
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Alternative Name
- Bid
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Background
- Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.
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UniProt
- P70444
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Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Target
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