CCR9 antibody (AA 306-334)

Catalog No. ABIN3030500

Product Details anti-CCR9 Antibody

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Binding Specificity: AA 306-334

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 306-334 from the human protein was used as the immunogen for this CCR9 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CCR9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CCR9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CCR9

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Alternative Name: CCR9 (CCR9 Products)

Synonyms: CC-CKR-9 antibody, CDw199 antibody, GPR-9-6 antibody, GPR28 antibody, A130091K22Rik antibody, Cmkbr10 antibody, C-C motif chemokine receptor 9 antibody, chemokine (C-C motif) receptor 9 antibody, CCR9 antibody, Ccr9 antibody

Background: The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.

UniProt: P51686