CCR9 antibody (AA 306-334)
Quick Overview for CCR9 antibody (AA 306-334) (ABIN3030500)
Target
See all CCR9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 306-334
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Purpose
- CCR9 Antibody
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse
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Purification
- Antigen affinity
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Immunogen
- A portion of amino acids 306-334 from the human protein was used as the immunogen for this CCR9 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the CCR9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the CCR9 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))
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Alternative Name
- CCR9
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Background
- The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.
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UniProt
- P51686
Target
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