CEBPB antibody (AA 271-298)

Catalog No. ABIN3030346

This Rabbit Polyclonal antibody specifically detects CEBPB in WB, ELISA, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for CEBPB antibody (AA 271-298) (ABIN3030346)

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEBPB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-CEBPB Antibody

Binding Specificity: AA 271-298

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine, Chicken

Purification: Purified

Immunogen: A portion of amino acids 271-298 from the human protein was used as the immunogen for this CEBPB antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CEBPB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CEBPB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CEBPB

Target: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Alternative Name: CEBPB

Background: CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. This protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, It can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.

UniProt: P17676

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation