CSF1R antibody (AA 940-971)

Catalog No. ABIN3030557

The Rabbit Polyclonal anti-CSF1R antibody has been validated for WB, ELISA, IHC and FACS. It is suitable to detect CSF1R in samples from Human.

Quick Overview for CSF1R antibody (AA 940-971) (ABIN3030557)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSF1R antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-CSF1R Antibody

Binding Specificity: AA 940-971

Purification: Purified

Immunogen: A portion of amino acids 940-971 from the human protein was used as the immunogen for this CSF1R antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the CSF1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CSF1R antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Alternative Name: CSF1R

Background: CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. This protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in the gene encoding CSF1R have been associated with a predisposition to myeloid malignancy.

UniProt: P07333

Pathways: RTK Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization