Cytokeratin 18 antibody (AA 401-430)

Catalog No. ABIN3031537

This Rabbit Polyclonal antibody specifically detects Cytokeratin 18 in WB, IHC, IF, FACS and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Cytokeratin 18 antibody (AA 401-430) (ABIN3031537)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 18 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA

Product Details anti-Cytokeratin 18 Antibody

Binding Specificity: AA 401-430

Purification: Purified

Immunogen: A portion of amino acids 401-430 from the human protein was used as the immunogen for this Cytokeratin-18 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Cytokeratin-18 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Cytokeratin-18 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Alternative Name: Cytokeratin-18

Background: KRT18 is the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament family. They are expressed in single layer epithelial tissues of the body. Mutations in its gene have been linked to cryptogenic cirrhosis.

UniProt: P05783

Pathways: Apoptosis, Caspase Cascade in Apoptosis