DKK1 antibody (AA 58-84)

Catalog No. ABIN3028615

This Rabbit Polyclonal antibody specifically detects DKK1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for DKK1 antibody (AA 58-84) (ABIN3028615)

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DKK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DKK1 Antibody

Binding Specificity: AA 58-84

Purpose: DKK-1 Antibody

Purification: Antigen affinity

Immunogen: A portion of amino acids 58-84 from the human protein was used as the immunogen for this DKK-1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the DKK-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the DKK-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Alternative Name: DKK-1

Background: DKK-1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

UniProt: O94907

Pathways: WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation