Fatty Acid Synthase antibody (AA 942-973)
Quick Overview for Fatty Acid Synthase antibody (AA 942-973) (ABIN3030916)
Target
See all Fatty Acid Synthase (FASN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 942-973
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Purification
- Purified
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Immunogen
- A portion of amino acids 942-973 from human Fatty acid synthase was used as the immunogen for this FASN antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the FASN antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:200,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the FASN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Fatty Acid Synthase (FASN)
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Alternative Name
- FASN
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Background
- FASN (Fatty acid synthase) is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
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UniProt
- P49327
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Pathways
- AMPK Signaling
Target
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