The Mouse Monoclonal anti-Fatty Acid Synthase antibody has been validated for WB, ELISA and IF. It is suitable to detect Fatty Acid Synthase in samples from Human and Mouse.
Titration of the Fatty Acid Synthase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:200,Western blot: 1:100
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the Fatty Acid Synthase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
Fatty Acid Synthase (FASN)
Alternative Name
Fatty Acid Synthase
Background
Fatty acid synthase is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.