Fatty Acid Synthase antibody (AA 942-973)

Catalog No. ABIN3030917

The Mouse Monoclonal anti-Fatty Acid Synthase antibody is suitable to detect Fatty Acid Synthase in samples from Human and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for Fatty Acid Synthase antibody (AA 942-973) (ABIN3030917)

Target: Fatty Acid Synthase (FASN)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Fatty Acid Synthase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 497CT15-2-5

Product Details anti-Fatty Acid Synthase Antibody

Binding Specificity: AA 942-973

Purification: Purified

Immunogen: A portion of amino acids 942-973 from human FASN was used as the immunogen for this Fatty Acid Synthase antibody.

Isotype: IgM

Application Details

Application Notes: Titration of the Fatty Acid Synthase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:200,Western blot: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Fatty Acid Synthase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Alternative Name: Fatty Acid Synthase

Background: Fatty acid synthase is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

UniProt: P49327

Pathways: AMPK Signaling