FUS antibody (AA 499-526)

Catalog No. ABIN3031006

This Rabbit Polyclonal antibody specifically detects FUS in WB, IHC, ELISA, IF and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for FUS antibody (AA 499-526) (ABIN3031006)

Target: FUS (Fused in Sarcoma (FUS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-FUS Antibody

Binding Specificity: AA 499-526

Cross-Reactivity (Details): Expected species reactivity: Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 499-526 from the human protein was used as the immunogen for this FUS antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the FUS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the FUS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for FUS

Target: FUS (Fused in Sarcoma (FUS))

Alternative Name: FUS

Background: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.

UniProt: P35637