HDAC3 antibody (AA 383-412)
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- Target See all HDAC3 Antibodies
- HDAC3 (Histone Deacetylase 3 (HDAC3))
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Binding Specificity
- AA 383-412
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HDAC3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Rat
- Purification
- Antigen affinity purified
- Immunogen
- A portion of amino acids 383-412 from the human protein was used as the immunogen for this HDAC3 antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product HDAC3 Primary Antibody
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- Application Notes
- Titration of the HDAC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the HDAC3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- HDAC3 (Histone Deacetylase 3 (HDAC3))
- Alternative Name
- HDAC3 (HDAC3 Products)
- Synonyms
- CG2128 antibody, DHDAC3 antibody, DmHDAC3 antibody, Dmel\\CG2128 antibody, Dromel_CG2128_FBtr0078767_hdac3_mORF antibody, HDAC antibody, HDAC3 antibody, Hdac 3 antibody, dHDAC3 antibody, dmHDA402 antibody, hdac3 antibody, HDm antibody, hd3 antibody, RPD3 antibody, XRpd3 antibody, rpd3-2 antibody, HD3 antibody, RPD3-2 antibody, AW537363 antibody, zgc:55927 antibody, Histone deacetylase 3 antibody, histone deacetylase 3 antibody, histone deacetylase 3 S homeolog antibody, HDAC3 antibody, hdac3 antibody, CNL05260 antibody, Hdac3 antibody, hdac3.S antibody
- Background
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq].
- UniProt
- O15379
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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