HIST1H2BD antibody (AA 1-30)

Catalog No. ABIN3031209

Product Details anti-HIST1H2BD Antibody

Target: HIST1H2BD (Histone Cluster 1, H2bd (HIST1H2BD))

Binding Specificity: AA 1-30

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H2BD antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity (Details): Expected species reactivity: Mouse, Rat, Bovine, Primate

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for this HIST1H2BD antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the HIST1H2BD antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HIST1H2BD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for HIST1H2BD

Target: HIST1H2BD (Histone Cluster 1, H2bd (HIST1H2BD))

Alternative Name: HIST1H2BD (HIST1H2BD Products)

Synonyms: HIST1H2BI antibody, H2B.1B antibody, H2B/b antibody, H2BFB antibody, HIRIP2 antibody, dJ221C16.6 antibody, histone cluster 1, H2bd antibody, histone cluster 1 H2B family member d antibody, HIST1H2BD antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq].

UniProt: P58876

Pathways: Telomere Maintenance