HSP27 antibody (AA 61-90)

Catalog No. ABIN3028697

The Rabbit Polyclonal anti-HSP27 antibody has been validated for WB and ELISA. It is suitable to detect HSP27 in samples from Human.

Quick Overview for HSP27 antibody (AA 61-90) (ABIN3028697)

Target: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP27 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HSP27 Antibody

Binding Specificity: AA 61-90

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 61-90 from human HSPB1 was used as the immunogen for this HSP27 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the HSP27 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HSP27 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSP27

Target: HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))

Alternative Name: HSP27

Background: In response to adverse changes in their environment, cells from many organisms increase the expression of a class of proteins referred to as heat shock or stress proteins. HSBP1/HSP27 exhibits rapid increased phosphorylation in response to various mitogens, tumor promoters (e.g. phorbol esters) and calcium ionophores, and high levels are associated with carcinoma of the breast and with endometrial adenocarcinomas.

UniProt: P04792

Pathways: MAPK Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling