HSP27 antibody (AA 108-136)
Quick Overview for HSP27 antibody (AA 108-136) (ABIN3031146)
Target
See all HSP27 (HSPB1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 108-136
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Cross-Reactivity (Details)
- Expected species reactivity: Mouse, Rat, Bovine
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Purification
- Purified
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Immunogen
- A portion of amino acids 108-136 from human HSPB1 was used as the immunogen for this HSP27 antibody.
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Isotype
- Ig Fraction
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Application Notes
- Titration of the HSP27 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the HSP27 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- HSP27 (HSPB1) (Heat Shock 27kDa Protein 1 (HSPB1))
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Alternative Name
- HSP27
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Background
- HSP27 is a chaperone of the sHsp (small heat shock protein) group among ubiquitin, α,-crystallin, Hsp20 and others. The common functions of sHsps are chaperone activity, thermotolerance, inhibition of apoptosis, regulation of cell development, and cell differentiation. They also take part in signal transduction. [Wiki]
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UniProt
- P04792
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Pathways
- MAPK Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, VEGF Signaling
Target
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