IGF2 antibody (AA 39-68)

Catalog No. ABIN3031346

The Rabbit Polyclonal anti-IGF2 antibody is suitable to detect IGF2 in samples from Human and Mouse. It has been validated for WB, IHC, ELISA and FACS.

Quick Overview for IGF2 antibody (AA 39-68) (ABIN3031346)

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Product Details anti-IGF2 Antibody

Binding Specificity: AA 39-68

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 39-68 from the human protein was used as the immunogen for this IGF2 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the IGF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IGF2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for IGF2

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Alternative Name: IGF2

Background: This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: P01344

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation