IKK-alpha /IKK-beta antibody (AA 155-184)

Catalog No. ABIN3028727

Product Details anti-IKK-alpha /IKK-beta Antibody

Target: IKK-alpha /IKK-beta

Binding Specificity: AA 155-184

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKK-alpha /IKK-beta antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): Expected species reactivity: Mouse, Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 155-184 from human IKKA was used as the immunogen for this IKK antibody. This sequence is 100% homologous with human IKKB.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the IKK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IKK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for IKK-alpha /IKK-beta

Target: IKK-alpha /IKK-beta

Alternative Name: IKK (Alpha/beta) (IKK-alpha /IKK-beta Products)

Background: IKKA is a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

UniProt: O15111