The Rabbit Polyclonal anti-IKK-alpha /IKK-beta antibody is suitable to detect IKK-alpha /IKK-beta in samples from Human. It has been validated for WB and ELISA.
Reactivity: Mouse
ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Titration of the IKK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the IKK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
IKK-alpha /IKK-beta
Alternative Name
IKK (Alpha/beta)
Background
IKKA is a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.