Interleukin 17a antibody (AA 61-87)

Catalog No. ABIN3031456

This Rabbit Polyclonal antibody specifically detects Interleukin 17a in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for Interleukin 17a antibody (AA 61-87) (ABIN3031456)

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Interleukin 17a antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Interleukin 17a Antibody

Binding Specificity: AA 61-87

Purpose: IL-17 Antibody

Cross-Reactivity (Details): Expected species reactivity: Bovine

Purification: Antigen affinity

Immunogen: A portion of amino acids 61-87 from human IL-17A was used as the immunogen for this IL-17 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the IL-17 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IL-17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Interleukin 17a

Target: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Alternative Name: IL-17A

Background: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

UniProt: Q16552