ITGA3 antibody (N-Term)

Catalog No. ABIN3031393

This Rabbit Polyclonal antibody specifically detects ITGA3 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ITGA3 antibody (N-Term) (ABIN3031393)

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ITGA3 Antibody

Binding Specificity: N-Term

Purification: Antigen affinity purified

Immunogen: This Integrin alpha 3 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 165-199 amino acids from the N-terminal region of human ITGA3.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Integrin alpha 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000-4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Integrin alpha 3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ITGA3

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Alternative Name: Integrin alpha 3

Background: Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex