ITGA7 antibody (C-Term)
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- Target See all ITGA7 Antibodies
- ITGA7 (Integrin, alpha 7 (ITGA7))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ITGA7 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antigen affinity purified
- Immunogen
- This Integrin alpha 7 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1149-1181 amino acids from the C-terminal region of human ITGA7.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ITGA7 Primary Antibody
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- Application Notes
- Titration of the Integrin alpha 7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000-8000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the Integrin alpha 7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- ITGA7 (Integrin, alpha 7 (ITGA7))
- Alternative Name
- Integrin alpha 7 (ITGA7 Products)
- Background
- Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
- UniProt
- Q13683
- Pathways
- Integrin Complex
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