ITGA7 antibody (AA 175-283)

Catalog No. ABIN7156450

Product Details anti-ITGA7 Antibody

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Binding Specificity: AA 175-283

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA7 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Integrin alpha-7 protein (175-283AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:200-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ITGA7

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Alternative Name: ITGA7 (ITGA7 Products)

Synonyms: [a]7 antibody, alpha7 antibody, integrin alpha 7 antibody, integrin subunit alpha 7 antibody, Itga7 antibody, ITGA7 antibody

Background:

Background: Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

Aliases: alpha 7 antibody, FLJ25220 antibody, Integrin alpha 7 antibody, Integrin alpha 7 chain antibody, Integrin alpha 7 heavy chain antibody, Integrin alpha 7 light chain antibody, Integrin alpha-7 70 kDa form antibody, ITA7_HUMAN antibody, ITGA 7 antibody, Itga7 antibody

UniProt: Q13683

Pathways: Integrin Complex