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MAVS antibody (AA 1-30)

MAVS Reactivity: Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031815
  • Target See all MAVS Antibodies
    MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
    Binding Specificity
    • 15
    • 12
    • 9
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30
    Reactivity
    • 49
    • 37
    • 4
    • 2
    • 1
    Mouse
    Host
    • 69
    • 7
    Rabbit
    Clonality
    • 71
    • 5
    Polyclonal
    Conjugate
    • 34
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAVS antibody is un-conjugated
    Application
    • 68
    • 36
    • 13
    • 13
    • 11
    • 9
    • 9
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 1-30 from the mouse protein was used as the immunogen for this Ips-1 antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MAVS Primary Antibody
  • Application Notes
    Titration of the Ips-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the Ips-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
    Alternative Name
    Ips-1 (MAVS Products)
    Synonyms
    CARDIF antibody, IPS-1 antibody, IPS1 antibody, VISA antibody, D430028G21Rik antibody, Visa antibody, cardif antibody, wu:fj20d04 antibody, zgc:158392 antibody, mitochondrial antiviral signaling protein antibody, MAVS antibody, Mavs antibody, mavs antibody
    Background
    Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
    UniProt
    Q8VCF0
    Pathways
    Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
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