IRF1 antibody (AA 260-286)

Catalog No. ABIN3031413

This anti-IRF1 antibody is a Rabbit Polyclonal antibody detecting IRF1 in WB and ELISA. Suitable for Human.

Quick Overview for IRF1 antibody (AA 260-286) (ABIN3031413)

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IRF1 Antibody

Binding Specificity: AA 260-286

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 260-286 from the human protein was used as the immunogen for this IRF1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the IRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the IRF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for IRF1

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Alternative Name: IRF1

Background: IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

UniProt: P10914

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy