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IRF1 antibody (AA 216-325)

IRF1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2E4 unconjugated
Catalog No. ABIN561520
  • Target See all IRF1 Antibodies
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Binding Specificity
    • 10
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 216-325
    Reactivity
    • 87
    • 48
    • 34
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    Human
    Host
    • 92
    • 5
    • 1
    • 1
    Mouse
    Clonality
    • 84
    • 15
    Monoclonal
    Conjugate
    • 48
    • 12
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRF1 antibody is un-conjugated
    Application
    • 87
    • 32
    • 14
    • 12
    • 11
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant IRF1.
    Sequence
    PMPSTSEATT DEDEEGKLPE DIMKLLEQSE WQPTNVDGKG YLLNEPGVQP TSVYGDFSCK EEPEIDSPGG DIGLSLQRVF TDLKNMDATW LDSLLTPVRL PSIQAIPCAP
    Cross-Reactivity
    Human
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    IRF1 (NP_002189, 216 a.a. ~ 325 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    2E4
    Isotype
    IgG2a
    Top Product
    Discover our top product IRF1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Bartlett, Slater, Glanville, Haas, Caramori, Casolari, Clarke, Message, Aniscenko, Kebadze, Zhu, Mallia, Mizgerd, Belvisi, Papi, Kotenko, Johnston, Edwards: "Defining critical roles for NF-?B p65 and type I interferon in innate immunity to rhinovirus." in: EMBO molecular medicine, Vol. 4, Issue 12, pp. 1244-60, (2012) (PubMed).

    Baumjohann, Okada, Ansel: "Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2089-92, (2011) (PubMed).

    Choi, Kageyama, Eto, Escobar, Johnston, Monticelli, Lao, Crotty: "ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6." in: Immunity, Vol. 34, Issue 6, pp. 932-46, (2011) (PubMed).

    Fazilleau, McHeyzer-Williams, Rosen, McHeyzer-Williams: "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding." in: Nature immunology, Vol. 10, Issue 4, pp. 375-84, (2009) (PubMed).

    Nurieva, Chung, Martinez, Yang, Tanaka, Matskevitch, Wang, Dong: "Bcl6 mediates the development of T follicular helper cells." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1001-5, (2009) (PubMed).

    Steffen, MacKay, Kerr, Tsuchiya, Hu, Fox, Dang, Johnston, Oakes, Tchao, Pak, Fields, Kennedy, Kaeberlein: "Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4." in: Cell, Vol. 133, Issue 2, pp. 292-302, (2008) (PubMed).

    Ye, Lista, Lo Coco, Knowles, Offit, Chaganti, Dalla-Favera: "Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma." in: Science (New York, N.Y.), Vol. 262, Issue 5134, pp. 747-50, (1993) (PubMed).

  • Target
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    Alternative Name
    IRF1 (IRF1 Products)
    Synonyms
    irf1 antibody, zgc:136945 antibody, IRF1 antibody, irf11 antibody, zgc:103566 antibody, IRF-1 antibody, MAR antibody, AU020929 antibody, Irf-1 antibody, interferon regulatory factor 1 antibody, interferon regulatory factor 1a antibody, interferon regulatory factor 1b antibody, IRF1 antibody, irf1a antibody, irf1b antibody, Irf1 antibody
    Background
    Full Gene Name: interferon regulatory factor 1
    Synonyms: IRF-1,MAR
    Gene ID
    3659
    NCBI Accession
    NM_002198
    Pathways
    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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