LOXL3 antibody (AA 715-744)

Catalog No. ABIN3031669

This Rabbit Polyclonal antibody specifically detects LOXL3 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for LOXL3 antibody (AA 715-744) (ABIN3031669)

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-LOXL3 Antibody

Binding Specificity: AA 715-744

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 715-744 from the human protein was used as the immunogen for this LOXL3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the LOXL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the LOXL3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for LOXL3

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Alternative Name: LOXL3

Background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined.

UniProt: P58215