LRRK1 antibody (AA 1981-2015)

Catalog No. ABIN3031606

This Rabbit Polyclonal antibody specifically detects LRRK1 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for LRRK1 antibody (AA 1981-2015) (ABIN3031606)

Target: LRRK1 (Leucine-Rich Repeat Kinase 1 (LRRK1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRK1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-LRRK1 Antibody

Binding Specificity: AA 1981-2015

Purification: Purified

Immunogen: A portion of amino acids 1981-2015 from the human protein was used as the immunogen for this LRRK1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the LRRK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the LRRK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for LRRK1

Target: LRRK1 (Leucine-Rich Repeat Kinase 1 (LRRK1))

Alternative Name: LRRK1

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

UniProt: Q38SD2