LRRK1 antibody (AA 361-410)

Catalog No. ABIN1533940

The Rabbit Polyclonal anti-LRRK1 antibody is suitable to detect LRRK1 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for LRRK1 antibody (AA 361-410) (ABIN1533940)

Target: LRRK1 (Leucine-Rich Repeat Kinase 1 (LRRK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRK1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-LRRK1 Antibody

Binding Specificity: AA 361-410

Purpose: LRRK1 Antibody

Specificity: LRRK1 Polyclonal Antibody detects endogenous levels of LRRK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human LRRK1. AA range:361-410

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for LRRK1

Target: LRRK1 (Leucine-Rich Repeat Kinase 1 (LRRK1))

Alternative Name: LRRK1

Background:

Synonyms: LRRK1, KIAA1790, Leucine-rich repeat serine/threonine-protein kinase 1

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats.,

Gene Name: LRRK1

Protein Name: Leucine-rich repeat serine/threonine-protein kinase 1

Molecular Weight: 227 kDa

Gene ID: 79705

OMIM: 610986

UniProt: Q38SD2