MAP4K4 antibody (AA 618-649)
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- Target See all MAP4K4 Antibodies
- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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Binding Specificity
- AA 618-649
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAP4K4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Purified
- Immunogen
- A portion of amino acids 618-649 from the human protein was used as the immunogen for this NIK antibody.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MAP4K4 Primary Antibody
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anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibody
MAP4K4 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 4A5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 866-1104) antibodyMAP4K4 Reactivity: Human WB, ELISA, IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 Reactivity: Human, Mouse WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 Reactivity: Human, Mouse, Rat WB, ELISA, IF, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 400-500) antibodyMAP4K4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4H9E7 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibodyMAP4K4 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2D4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 287-336) antibodyMAP4K4 Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow, Pig, Bat, Chicken, Xenopus laevis WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (N-Term) antibodyMAP4K4 Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 Reactivity: Human, Mouse WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (pSer629) antibodyMAP4K4 Reactivity: Human DB Host: Rabbit Polyclonal RB12877 unconjugated
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- Application Notes
- Titration of the NIK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot the NIK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Target
- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
- Alternative Name
- NIK (Nck-Interacting Kinase) (MAP4K4 Products)
- Synonyms
- FLH21957 antibody, HGK antibody, MEKKK4 antibody, NIK antibody, 9430080K19Rik antibody, AU043147 antibody, AU045934 antibody, AW046177 antibody, Nik antibody, mitogen-activated protein kinase kinase kinase kinase 4 antibody, MAP4K4 antibody, Map4k4 antibody
- Background
- HGK/NIK, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK/NIK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.
- UniProt
- O95819
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