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NKX3-1 antibody (AA 3-1)

The Rabbit Polyclonal anti-NKX3-1 antibody has been validated for WB and ELISA. It is suitable to detect NKX3-1 in samples from Mouse.
Catalog No. ABIN3032012

Quick Overview for NKX3-1 antibody (AA 3-1) (ABIN3032012)

Target

See all NKX3-1 Antibodies
NKX3-1 (NK3 Homeobox 1 (NKX3-1))

Reactivity

  • 117
  • 18
  • 6
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Mouse

Host

  • 73
  • 52
  • 1
Rabbit

Clonality

  • 76
  • 50
Polyclonal

Conjugate

  • 57
  • 10
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This NKX3-1 antibody is un-conjugated

Application

  • 66
  • 52
  • 50
  • 39
  • 8
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), ELISA
  • Binding Specificity

    • 58
    • 8
    • 8
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 3-1

    Purification

    Antigen affinity purified

    Immunogen

    A portion of amino acids 3-1 from the mouse protein was used as the immunogen for this Nkx3.1 antibody.

    Isotype

    Ig Fraction
  • Application Notes

    Titration of the Nkx3.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Aliquot the Nkx3.1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target

    NKX3-1 (NK3 Homeobox 1 (NKX3-1))

    Alternative Name

    Nkx3.1

    Background

    Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands). Essential for appropriate differentiation and secretory function of the bulbourethral gland.

    UniProt

    P97436

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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