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NKX3-1 antibody

NKX3-1 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 4H4 unconjugated
Catalog No. ABIN969316
  • Target See all NKX3-1 Antibodies
    NKX3-1 (NK3 Homeobox 1 (NKX3-1))
    Reactivity
    • 70
    • 19
    • 6
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 57
    • 22
    • 1
    Mouse
    Clonality
    • 55
    • 25
    Monoclonal
    Conjugate
    • 46
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NKX3-1 antibody is un-conjugated
    Application
    • 55
    • 44
    • 14
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human NKX3A expressed in E. coli.
    Clone
    4H4
    Isotype
    IgG2b
    Top Product
    Discover our top product NKX3-1 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Zhang, Liu, Zhang, Guan, Chen, Cui, Liu, Jiang: "Gene expression profiles in the PC-3 human prostate cancer cells induced by NKX3.1." in: Molecular biology reports, Vol. 37, Issue 3, pp. 1505-12, (2010) (PubMed).

    Lee, Jadhav, Ayer, Rojas, Hyong, Lekic, Stier, Martin, Zhang: "The antioxidant effects of melatonin in surgical brain injury in rats." in: Acta neurochirurgica. Supplement, Vol. 102, pp. 367-71, (2009) (PubMed).

    Zhang, Fillmore, Zimmer: "Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factor." in: Experimental biology and medicine (Maywood, N.J.), Vol. 233, Issue 3, pp. 297-309, (2008) (PubMed).

    Jiang, Yu, Zhang, Chen, Liu, Hu, Zhang: "p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line." in: Experimental & molecular medicine, Vol. 38, Issue 6, pp. 625-33, (2007) (PubMed).

  • Target
    NKX3-1 (NK3 Homeobox 1 (NKX3-1))
    Alternative Name
    NKX3A (NKX3-1 Products)
    Synonyms
    Xbagpipe antibody, Xbap antibody, bagpipe antibody, koza antibody, nkx3-1 antibody, nkx3.1 antibody, si:ch211-67o1.2 antibody, nkx3a antibody, MGC53041 antibody, MGC97890 antibody, Bax antibody, NKX3.1 antibody, NKX3A antibody, Nkx-3.1 antibody, BAPX2 antibody, NKX3 antibody, NK3 homeobox 1 L homeolog antibody, NK3 homeobox 1 antibody, NK-3 transcription factor, locus 1 (Drosophila) antibody, nkx3-1.L antibody, NKX3-1 antibody, nkx3-1 antibody, Nkx3-1 antibody
    Background

    Description: Nkx3.1 is a transcription factor that may play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in the prostate. It has been thought to be one of the target genes of the 8p21 loss of heterozygosity, common in prostate cancer. But neither disruption of the coding region of the gene, nor mutations have been found in prostate cancer.

    Aliases: NKX3, BAPX2, NKX3A, NKX3.1, NKX3-1

    Molecular Weight
    26.3 kDa
    Gene ID
    4824
    HGNC
    4824
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Positive Regulation of Endopeptidase Activity, Positive Regulation of Response to DNA Damage Stimulus
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