NKX6-1 antibody (AA 285-314)

Catalog No. ABIN3028877

The Rabbit Polyclonal anti-NKX6-1 antibody has been validated for WB and ELISA. It is suitable to detect NKX6-1 in samples from Human and Mouse.

Quick Overview for NKX6-1 antibody (AA 285-314) (ABIN3028877)

Target: NKX6-1 (NK6 Homeobox 1 (NKX6-1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX6-1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NKX6-1 Antibody

Binding Specificity: AA 285-314

Cross-Reactivity (Details): Expected species reactivity: Rat

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 285-314 from the human protein was used as the immunogen for this NKX6.1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NKX6.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NKX6.1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NKX6-1

Target: NKX6-1 (NK6 Homeobox 1 (NKX6-1))

Alternative Name: NKX6.1

Background: In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. [OMIM].

UniProt: P78426

Pathways: Dopaminergic Neurogenesis, Positive Regulation of Peptide Hormone Secretion