NKX6-1 antibody (C-Term)

Catalog No. ABIN953718

Product Details anti-NKX6-1 Antibody

Target: NKX6-1 (NK6 Homeobox 1 (NKX6-1))

Binding Specificity: AA 284-314, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKX6-1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes NKX6-1 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 284-314aa) of human NKX6-1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for NKX6-1

Target: NKX6-1 (NK6 Homeobox 1 (NKX6-1))

Alternative Name: NKX6-1 (NKX6-1 Products)

Synonyms: nkx6a antibody, nkx6.1 antibody, NKX6.1 antibody, NKX6A antibody, zgc:92879 antibody, Nkx6.1 antibody, Nkx61 antibody, Nkx6a antibody, NK6 homeobox 1 antibody, NK6 homeobox 1 L homeolog antibody, nkx6-1 antibody, NKX6-1 antibody, nkx6.1 antibody, nkx6-1.L antibody, Nkx6-1 antibody

Background: In the pancreas, NKX6-1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes. [Iype et al., 2004, PubMed 15056733]Synonyms: Homeobox protein Nkx-6.1, NKX6A

Gene ID: 4825

NCBI Accession: NP_006159

Pathways: Dopaminergic Neurogenesis, Positive Regulation of Peptide Hormone Secretion