NADPH Oxidase 4 antibody (AA 124-153)

Catalog No. ABIN3031934

The Rabbit Polyclonal anti-NADPH Oxidase 4 antibody has been validated for WB, ELISA and IHC. It is suitable to detect NADPH Oxidase 4 in samples from Human.

Quick Overview for NADPH Oxidase 4 antibody (AA 124-153) (ABIN3031934)

Target: NADPH Oxidase 4 (NOX4)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NADPH Oxidase 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NADPH Oxidase 4 Antibody

Binding Specificity: AA 124-153

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 124-153 from the human protein was used as the immunogen for this NOX4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the NOX4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the NOX4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Alternative Name: NOX4

Background: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration